发明申请
- 专利标题: METHODS OF REDUCTION OF INTERPATIENT VARIABILITY
- 专利标题(中): 减少互补性变异的方法
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申请号: US12422834申请日: 2009-04-13
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公开(公告)号: US20100076087A1公开(公告)日: 2010-03-25
- 发明人: Thomas G. Gant , Sepehr Sarshar
- 申请人: Thomas G. Gant , Sepehr Sarshar
- 申请人地址: US CA Vista
- 专利权人: Auspex Pharmaceuticals, Inc.
- 当前专利权人: Auspex Pharmaceuticals, Inc.
- 当前专利权人地址: US CA Vista
- 主分类号: A61K31/137
- IPC分类号: A61K31/137 ; A61P25/24
摘要:
Disclosed herein are methods for the reduction of inter-patient variability of a drug, such as in one or more parameters including half-life (t1/2), maximum plasma concentration (Cmax), time at maximal plasma concentration (Tmax), area under the time-versus-concentration curve (AUC). Also provided are methods of reducing side effects associated with drugs.