发明申请
US20100080806A1 Anti-human trail receptor dr5 monoclonal antibody (ad5-10), method thereof and use of the same 有权
抗人类轨迹受体dr5单克隆抗体(ad5-10),其方法及其用途

  • 专利标题: Anti-human trail receptor dr5 monoclonal antibody (ad5-10), method thereof and use of the same
  • 专利标题(中): 抗人类轨迹受体dr5单克隆抗体(ad5-10),其方法及其用途
  • 申请号: US11596271
    申请日: 2005-07-03
  • 公开(公告)号: US20100080806A1
    公开(公告)日: 2010-04-01
  • 发明人: Yanxin LiuYabin GuoDexian Zheng
  • 申请人: Yanxin LiuYabin GuoDexian Zheng
  • 优先权: CN200410070093.1 20040819
  • 国际申请: PCT/CN05/00271 WO 20050703
  • 主分类号: A61K39/395
  • IPC分类号: A61K39/395 C07K16/18 C12N5/16 A61K35/00
Anti-human trail receptor dr5 monoclonal antibody (ad5-10), method thereof and use of the same
摘要:
The present invention discloses a monoclonal antibody against the extracellular domain of human tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 (death receptor 5), The present invention also provides a method of producing the monoclonal antibody, amino acid sequences of the variable regions of the monoclonal antibody's heavy chain and light chain, as well as use of the monoclonal antibody for preparation of a medicament in the treatment of various cancers and/or AIDS.
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