发明申请
US20100093007A1 Method of Diagnosis of Tuberculosis Related Immune Restoration Syndrome (IRS)
审中-公开
结核病相关免疫恢复综合征（IRS）诊断方法
- 专利标题： Method of Diagnosis of Tuberculosis Related Immune Restoration Syndrome (IRS)
- 专利标题（中）： 结核病相关免疫恢复综合征（IRS）诊断方法
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申请号： US11992562申请日： 2006-09-07
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公开(公告)号： US20100093007A1公开(公告)日： 2010-04-15
- 发明人: Brigitte Autran , Anne Bourgarit , Guislaine Carcelain , Valérie Martinez , Brigitte Gicquel , Daniel Sereni
- 申请人： Brigitte Autran , Anne Bourgarit , Guislaine Carcelain , Valérie Martinez , Brigitte Gicquel , Daniel Sereni
- 申请人地址： FR Paris
- 专利权人： Institut National de la Sante et de la Recherche Medicale (INSERM)
- 当前专利权人： Institut National de la Sante et de la Recherche Medicale (INSERM)
- 当前专利权人地址： FR Paris
- 优先权： EP05291998.2 20050927
- 国际申请： PCT/EP2006/066152 WO 20060907
- 主分类号： G01N33/566
- IPC分类号： G01N33/566
摘要：
The present invention relates to a method and kit of diagnosis of Immune Restoration Syndrome associated with tuberculosis (TB-IRS) in patients infected with tuberculosis (TB) as well as in HIV co-infected patients comprising detecting an acute increase in Th1 response following exposure to mycobacterial extract, referred as tuberculin or PPD (Purified Protein Derivative) as well as to the 16 kDa protein, but not to ESAT-6 or CFP-10, two antigens from mycobacterium tuberculosis.
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