发明申请
- 专利标题: DIAMINE DERIVATIVES
- 专利标题(中): DIAMINE衍生物
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申请号: US12259496申请日: 2008-12-30
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公开(公告)号: US20100093785A1公开(公告)日: 2010-04-15
- 发明人: Toshiharu Ohta , Satoshi Komoriya , Toshiharu Yoshino , Kouichi Uoto , Yumi Nakamoto , Hiroyuki Naito , Akiyoshi Mochizuki , Tsutomu Nagata , Hideyuki Kanno , Noriyasu Haginoya , Kenji Yoshikawa , Masatoshi Nagamochi , Syozo Kobayashi , Makoto Ono
- 申请人: Toshiharu Ohta , Satoshi Komoriya , Toshiharu Yoshino , Kouichi Uoto , Yumi Nakamoto , Hiroyuki Naito , Akiyoshi Mochizuki , Tsutomu Nagata , Hideyuki Kanno , Noriyasu Haginoya , Kenji Yoshikawa , Masatoshi Nagamochi , Syozo Kobayashi , Makoto Ono
- 申请人地址: JP Tokyo
- 专利权人: DAIICHI PHARMACEUTICAL CO., LTD.
- 当前专利权人: DAIICHI PHARMACEUTICAL CO., LTD.
- 当前专利权人地址: JP Tokyo
- 优先权: JP2001-187105 20010620; JP2001-243046 20010809; JP2001-311808 20011009; JP2001-398708 20011228
- 主分类号: A61K31/437
- IPC分类号: A61K31/437
摘要:
A compound represented by the general formula (1): -Q1-Q2-T0-N(R1)-Q3-(R2)T1Q4 (1) wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof.The compound is useful as an agent for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.
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