发明申请
- 专利标题: COMPOUNDS AND METHODS FOR MODULATING PROTEIN EXPRESSION
- 专利标题(中): 化合物和调节蛋白质表达的方法
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申请号: US12524778申请日: 2008-01-29
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公开(公告)号: US20100093836A1公开(公告)日: 2010-04-15
- 发明人: Balkrishen Bhat , Eric E. Swayze , Walter F. Lima , Stanley T. Crooke
- 申请人: Balkrishen Bhat , Eric E. Swayze , Walter F. Lima , Stanley T. Crooke
- 申请人地址: US CA Carlsbad
- 专利权人: ISIS Pharmaceuticals, Inc
- 当前专利权人: ISIS Pharmaceuticals, Inc
- 当前专利权人地址: US CA Carlsbad
- 国际申请: PCT/US08/52361 WO 20080129
- 主分类号: A61K31/7088
- IPC分类号: A61K31/7088 ; C07H19/04 ; C12N5/02
摘要:
The present invention includes compositions and methods useful for modulating protein expression. In certain embodiments, the present invention includes oligomeric compounds comprising modified nucleosides and modified internucleoside linkages.
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