A method and an apparatus of subchannelization is provided. The method includes receiving information indicating the number of physical resource unit (PRU) sets allocated to a subband from a base station, and mapping PRUs of a physical region to a subband PRU or a miniband PRU in a granularity of the PRU set according to the received information, wherein the subband PRU is allocated with at least one subband comprising a first number of contiguous PRUs, the miniband PRU is allocated with at least one miniband comprising a second number of PRUs, and the PRU set comprises PRUs whose number is equal to the number of PRUs included in one subband. Subchannelization can be effectively achieved while maintaining a frequency selective scheduling gain and a frequency diversity gain to the maximum extent possible.