发明申请
US20100113428A1 DIAZABICYCLIC ARYL DERIVATIVES AS CHOLINERGIC RECEPTOR MODULATORS
失效
作为胆碱受体调节剂的二亚氨基衍生物
- 专利标题： DIAZABICYCLIC ARYL DERIVATIVES AS CHOLINERGIC RECEPTOR MODULATORS
- 专利标题（中）： 作为胆碱受体调节剂的二亚氨基衍生物
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申请号： US12633505申请日： 2009-12-08
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公开(公告)号： US20100113428A1公开(公告)日： 2010-05-06
- 发明人: Dan PETERS , Gunnar M. OLSEN , Elsebet Østergaard NIELSEN , Tino Dyhring JØRGENSEN , Daniel B. TIMMERMANN
- 申请人： Dan PETERS , Gunnar M. OLSEN , Elsebet Østergaard NIELSEN , Tino Dyhring JØRGENSEN , Daniel B. TIMMERMANN
- 优先权： DKPA200400171 20040204; DKPA200400812 20040524
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; C07D243/14 ; A61P37/02 ; A61P25/34 ; A61P25/28 ; A61P25/02
摘要：
This invention relates to novel diazabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
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