发明申请
US20100113541A1 CRYSTAL FORMS OF 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL
审中-公开
2-(3-氟-4-羟基苯基)-7-乙烯基-1,3-苯并恶唑-5-OL的晶体形式
- 专利标题: CRYSTAL FORMS OF 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL
- 专利标题(中): 2-(3-氟-4-羟基苯基)-7-乙烯基-1,3-苯并恶唑-5-OL的晶体形式
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申请号: US12642273申请日: 2009-12-18
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公开(公告)号: US20100113541A1公开(公告)日: 2010-05-06
- 发明人: Abdolsamad TADAYON , Silvio IERA , Hong WEN , Marc S. TESCONI , Mannching Sherry KU
- 申请人: Abdolsamad TADAYON , Silvio IERA , Hong WEN , Marc S. TESCONI , Mannching Sherry KU
- 申请人地址: US NJ Madison
- 专利权人: Wyeth LLC
- 当前专利权人: Wyeth LLC
- 当前专利权人地址: US NJ Madison
- 主分类号: A61K31/423
- IPC分类号: A61K31/423 ; C07D263/56 ; A61P25/28 ; A61P1/00 ; A61P35/00 ; A61P19/02 ; A61P15/02 ; A61P13/02 ; A61P11/06 ; A61P3/10
摘要:
The present invention is directed to monohydrate and anhydrate crystal forms of 2-(3-fluoro-4-hydroxyphenyl)-7-vinyl-1,3-benzoxazol-5-ol, an estrogenic receptor modulator useful in the treatment of, for example, diseases related to abnormal levels of estrogen.