发明申请
- 专利标题： IDENTIFICATION AND VERIFICATION OF METHYLATION MARKER SEQUENCES
- 专利标题（中）： 甲基标记序列的鉴定和验证
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申请号： US12489502申请日： 2009-06-23
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公开(公告)号： US20100136541A1公开(公告)日： 2010-06-03
- 发明人: Chris Beard , Chris Burgess , Allison Gannon , Jeanne Harvey , John F. Lechner , Zheng Li
- 申请人： Chris Beard , Chris Burgess , Allison Gannon , Jeanne Harvey , John F. Lechner , Zheng Li
- 申请人地址： US NY Tarrytown
- 专利权人： Siemens Healthcare Diagnostics Inc.
- 当前专利权人： Siemens Healthcare Diagnostics Inc.
- 当前专利权人地址： US NY Tarrytown
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The present invention relates to methods for identifying among the genes that are down-regulated in cells or tissues having disease including cancer, the CpG sites within the CpG islands of said genes, wherein the identified CpG sites show great potential for diagnostic utility. In another aspect, the present invention also provides methods of using the selected CpG sites for purposes of diagnosis, prognosis, staging, assessing or monitoring the therapy of or recovery from a disease such as cancer.
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