发明申请
US20100137383A1 NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
有权
作为金属螯合剂的DESAZADESFERROTHIOCIN聚醚类似物的新型盐和聚合物
- 专利标题： NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
- 专利标题（中）： 作为金属螯合剂的DESAZADESFERROTHIOCIN聚醚类似物的新型盐和聚合物
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申请号： US12502559申请日： 2009-07-14
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公开(公告)号： US20100137383A1公开(公告)日： 2010-06-03
- 发明人: Amy E. Tapper , Hugh Y. Rienhoff, JR. , Stephan D. Parent , Patricia Andres , Jason A. Hanko , Huamin Zhang
- 申请人： Amy E. Tapper , Hugh Y. Rienhoff, JR. , Stephan D. Parent , Patricia Andres , Jason A. Hanko , Huamin Zhang
- 申请人地址： US CA San Carlos
- 专利权人： FERROKIN BIOSCIENCES, INC.
- 当前专利权人： FERROKIN BIOSCIENCES, INC.
- 当前专利权人地址： US CA San Carlos
- 主分类号： A61K31/426
- IPC分类号： A61K31/426 ; C07D277/12 ; A61P43/00 ; A61P7/06
摘要：
Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
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