Invention Application
US20100144035A1 Delivery system for nucleic acids using cationic polymer conjugates
有权
使用阳离子聚合物共轭物的核酸递送系统
- Patent Title: Delivery system for nucleic acids using cationic polymer conjugates
- Patent Title (中): 使用阳离子聚合物共轭物的核酸递送系统
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Application No.: US12733061Application Date: 2008-04-04
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Publication No.: US20100144035A1Publication Date: 2010-06-10
- Inventor: Yu-Kyoung Oh , Hyun-Gu Kang , Ji-Seok Kim , Jiang Ge , Ki-Su Kim , Ki-Tae Park , Su-Eun Han , Ga-Yong Shim , II-Hwan Cho , Sei-Kwang Hahn
- Applicant: Yu-Kyoung Oh , Hyun-Gu Kang , Ji-Seok Kim , Jiang Ge , Ki-Su Kim , Ki-Tae Park , Su-Eun Han , Ga-Yong Shim , II-Hwan Cho , Sei-Kwang Hahn
- Assignee: Postech Academy-Industry Foundation,Korea University Industry and Academy Collaboration Foundation
- Current Assignee: Postech Academy-Industry Foundation,Korea University Industry and Academy Collaboration Foundation
- Priority: KR10-2007-0080276 20070809
- International Application: PCT/KR2008/001914 WO 20080404
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C08G63/91
Abstract:
The present invention relates to a delivery system for nucleic acid using a cationic polymer conjugate, and more specifically relates to a delivery system for nucleic acid comprising a cationic polymer conjugate prepared by conjugating hyaluronic acid or its derivative and polyethyleneimine, and a composition of delivering a nucleic acid into mammalian cell comprising a complex of the nucleic acid and a cationic polymer conjugate with electrostatic binding.
Public/Granted literature
- US08318856B2 Nucleic acid delivery system comprising conjugates of PEI and hyaluronic acid Public/Granted day:2012-11-27
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