发明申请
- 专利标题： Small-molecule agonists for type-2 orexin receptor
- 专利标题（中）： 2型食欲素受体的小分子激动剂
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申请号： US12478753申请日： 2009-06-04
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公开(公告)号： US20100150840A1公开(公告)日： 2010-06-17
- 发明人: Masashi Yanagisawa
- 申请人： Masashi Yanagisawa
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/4168 ; A61K31/506 ; A61K31/496 ; A61P3/04 ; A61K49/00 ; C12Q1/02
摘要：
Methods and compositions for agonizing a type-2 orexin receptor (OX2R) in a cell determined to be in need thereof, including the general method of (a) administering to a subject a cyclic guanidinyl OX2R agonist and (b) detecting a resultant enhanced wakefulness or increased resistance to diet-induced accumulation of body fat, or abbreviated recovery from general anesthesia or jet lag.
公开/授权文献
- US08258163B2 Small-molecule agonists for type-2 orexin receptor 公开/授权日：2012-09-04
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