发明申请
US20100152187A1 AMINOTHIAZOLE DERIVATIVES AS HUMAN STEAROYL-COA DESATURASE INHIBITORS
失效
作为人类硬脂酸脱乙酰酶抑制剂的氨基噻唑衍生物
- 专利标题： AMINOTHIAZOLE DERIVATIVES AS HUMAN STEAROYL-COA DESATURASE INHIBITORS
- 专利标题（中）： 作为人类硬脂酸脱乙酰酶抑制剂的氨基噻唑衍生物
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申请号： US11916243申请日： 2006-06-05
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公开(公告)号： US20100152187A1公开(公告)日： 2010-06-17
- 发明人: Jianmin Fu , Duanjie Hou , Rajender Kamboj , Vishnumurthy Kodumuru , Natalia Pokrovskaia , Vandna Raina , Shaoyi Sun , Serguei Sviridov , Zaihui Zhang
- 申请人： Jianmin Fu , Duanjie Hou , Rajender Kamboj , Vishnumurthy Kodumuru , Natalia Pokrovskaia , Vandna Raina , Shaoyi Sun , Serguei Sviridov , Zaihui Zhang
- 申请人地址： CA BC Burnaby
- 专利权人： XENON PHARMACEUTICALS INC.
- 当前专利权人： XENON PHARMACEUTICALS INC.
- 当前专利权人地址： CA BC Burnaby
- 国际申请： PCT/US2006/021660 WO 20060605
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C12N9/99 ; A61K31/4439 ; A61K31/426 ; A61P3/10 ; A61P3/04 ; A61P9/10
摘要：
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I), where V, W, R1, R2, R3 and R4 are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
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