发明申请
US20100152251A1 PYRIDINE, QUINOLINE, AND ISOQUINOLINE N-OXIDES AS KINASE INHIBITORS
有权
吡啶，喹啉和异喹啉N-氧化物作为激酶抑制剂
- 专利标题： PYRIDINE, QUINOLINE, AND ISOQUINOLINE N-OXIDES AS KINASE INHIBITORS
- 专利标题（中）： 吡啶，喹啉和异喹啉N-氧化物作为激酶抑制剂
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申请号： US12692845申请日： 2010-01-25
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公开(公告)号： US20100152251A1公开(公告)日： 2010-06-17
- 发明人: Jacques DUMAS , William J. Scott , Bernd Riedl
- 申请人： Jacques DUMAS , William J. Scott , Bernd Riedl
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; A61P35/00 ; A61P29/00
摘要：
This invention relates to urea compounds containing a pyridine, quinoline, or isoquinoline functionality which is oxidized at the nitrogen heteroatom and which are useful in the treatment of (i) raf mediated diseases, for example, cancer, (ii) p38 mediated diseases such as inflammation and osteoporosis, and (iii) VEGF mediated diseases such as angiogenesis disorders.