发明申请
- 专利标题： 4-ANILINO QUINAZOLINE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS
- 专利标题（中）： 4-苯胺喹诺酮衍生物作为抗增生剂
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申请号： US12706675申请日： 2010-02-16
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公开(公告)号： US20100152442A1公开(公告)日： 2010-06-17
- 发明人: Robert Hugh Bradbury , Laurent Francois Andre Hennequin , Jason Grant Kettle
- 申请人： Robert Hugh Bradbury , Laurent Francois Andre Hennequin , Jason Grant Kettle
- 专利权人： Astrazeneca AB
- 当前专利权人： Astrazeneca AB
- 优先权： GB0207323.7 20020328; GB0230086.1 20021224; GB0301916.3 20030128
- 主分类号： C07D413/14
- IPC分类号： C07D413/14 ; C07D403/12
摘要：
The invention concerns quinazoline derivatives of Formula (I) wherein each of Q1, Z, R1 and Q2 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosine kinases.
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