An information handling system includes a processor with a bifurcated unified issue queue that may perform unified issue queue VSU store instruction dependency operations. The bifurcated unified issue queue BUIQ maintains VSU store instructions in the form of internal operations data. The BUIQ includes a unified issue queue UIQ 0 and a unified issue queue UIQ 1. The BUIQ may manage a particular VSU store instruction from one UIQ to determine data dependencies and employ the other UIQ to determine address dependencies of that particular VSU store instruction. The UIQs employ a dependency matrix including a dependency array. The dependency array data maintains both data and address dependency information. The particular VSU store instruction issues to execution units such as VSUs for data dependency information and load store units (LSUs) for address dependency information. A particular VSU store instruction may execute to provide data dependency information independent of address dependency information.