发明申请
US20100166746A1 HIGH POTENCY RECOMBINANT ANTIBODIES, METHODS FOR PRODUCING THEM AND USE IN CANCER THERAPY
审中-公开
高分辨率重组抗体，其制备方法和用于癌症治疗
- 专利标题： HIGH POTENCY RECOMBINANT ANTIBODIES, METHODS FOR PRODUCING THEM AND USE IN CANCER THERAPY
- 专利标题（中）： 高分辨率重组抗体，其制备方法和用于癌症治疗
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申请号： US12517300申请日： 2007-12-04
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公开(公告)号： US20100166746A1公开(公告)日： 2010-07-01
- 发明人: Partha Chowdhury , Herren Wu , Laura Richman
- 申请人： Partha Chowdhury , Herren Wu , Laura Richman
- 申请人地址： US MD Gaithersburg
- 专利权人： Medlmmune Way
- 当前专利权人： Medlmmune Way
- 当前专利权人地址： US MD Gaithersburg
- 国际申请： PCT/US07/24775 WO 20071204
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/30 ; A61P35/00
摘要：
The present invention contemplates improved recombinant anti-tumor antibodies having faster Kon and faster Koff rates, resulting in a uniform tumor penetrance, as compared to the same recombinant anti-tumor antibody without said faster Kon and faster Koff rates, and methods of improving the same.
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