发明申请
US20100167939A1 MULTIGENE ASSAY TO PREDICT OUTCOME IN AN INDIVIDUAL WITH GLIOBLASTOMA
审中-公开
多元素测定以预测个体与GLIOBLASTOMA的结果
- 专利标题： MULTIGENE ASSAY TO PREDICT OUTCOME IN AN INDIVIDUAL WITH GLIOBLASTOMA
- 专利标题（中）： 多元素测定以预测个体与GLIOBLASTOMA的结果
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申请号： US12529628申请日： 2008-02-29
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公开(公告)号： US20100167939A1公开(公告)日： 2010-07-01
- 发明人: Kenneth Aldape , Howard Colman , Li Zhang
- 申请人： Kenneth Aldape , Howard Colman , Li Zhang
- 国际申请： PCT/US08/55472 WO 20080229
- 主分类号： C40B30/00
- IPC分类号： C40B30/00 ; C12Q1/68 ; C12Q1/02 ; C40B40/06
摘要：
The present invention concerns prognosis for glioblastoma and/or assessment of the response of an individual to therapy for glioblastoma treatment. In particular, expression analysis of two or more specific genes provided in the invention is determined to predict outcome for the individual and/or to predict if the individual will respond to therapy, such as chemoradiation, for example. In specific embodiments, a multigene set from a sample from the individual is compared to a reference set of housekeeping genes.
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