发明申请
- 专利标题: COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS
- 专利标题(中): 化合物和组合物作为激酶抑制剂
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申请号: US12518831申请日: 2007-12-11
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公开(公告)号: US20100168182A1公开(公告)日: 2010-07-01
- 发明人: Yuan Mi , Pamela Albaugh , Yi Fan , Ha-Soon Choi , Zuosheng Liu , Shenlin Huang
- 申请人: Yuan Mi , Pamela Albaugh , Yi Fan , Ha-Soon Choi , Zuosheng Liu , Shenlin Huang
- 申请人地址: BM Hamilton
- 专利权人: IRM LLC
- 当前专利权人: IRM LLC
- 当前专利权人地址: BM Hamilton
- 国际申请: PCT/US2007/025447 WO 20071211
- 主分类号: A61K31/404
- IPC分类号: A61K31/404 ; A61K31/4439 ; A61K31/427 ; A61K31/422 ; A61K31/4178 ; A61K31/4155 ; C07D401/14 ; C07D417/14 ; C07D413/14 ; C07D403/14 ; C07D403/06 ; A61P35/00 ; C07D405/14
摘要:
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly TrkA, TrkB, TrkC, PDGFR and c-kit.