发明申请
US20100168221A1 PHARMACEUTICAL COMPOSITION FOR TREATING HEPATITIS B VIRUS AND HEALTH FOOD PRODUCT HAVING HEPATITIS B VIRUS INHIBITING EFFECTS
审中-公开
用于治疗乙型肝炎病毒和具有乙型肝炎病毒抑制作用的健康食品的药物组合物
- 专利标题： PHARMACEUTICAL COMPOSITION FOR TREATING HEPATITIS B VIRUS AND HEALTH FOOD PRODUCT HAVING HEPATITIS B VIRUS INHIBITING EFFECTS
- 专利标题（中）： 用于治疗乙型肝炎病毒和具有乙型肝炎病毒抑制作用的健康食品的药物组合物
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申请号： US12648986申请日： 2009-12-29
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公开(公告)号： US20100168221A1公开(公告)日： 2010-07-01
- 发明人: Lain-Tze LEE , Shau-Feng Chang , Chia-Yu Lin , Hui-Yen Wu , Shu-Feng Chen , Jinun-Ban Yeh
- 申请人： Lain-Tze LEE , Shau-Feng Chang , Chia-Yu Lin , Hui-Yen Wu , Shu-Feng Chen , Jinun-Ban Yeh
- 申请人地址： TW Hsinchu
- 专利权人： INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
- 当前专利权人： INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
- 当前专利权人地址： TW Hsinchu
- 优先权： TW097151799 20081231
- 主分类号： A61K31/352
- IPC分类号： A61K31/352 ; A61P31/12
摘要：
The invention provides a pharmaceutical composition for treating hepatitis B, including: an effective amount of proanthocyanidins; and a pharmaceutically acceptable carrier or salt, wherein a formula of the monomer of the proanthocyanidins is shown in the following: , wherein R1 is OCH3, R2 is OH and R3 is H, or R1 is OH and R2 and R3 both are H, or R1 and R2 both are OH and R3 is H, or R1, R2 and R3 all are OH, and R4 is 3-(α)-OH, 3-(β)-OH, 3-(α)-O-sugar or 3-(β)-O-sugar. Bonding between adjacent monomers take place at C4, C8 Carbon-carbon bond or C2, C7 oxygen bond of A type or C4, C8 or C4, C6 Carbon-carbon bond of B type or C type of proanthocyanidins. And the polymerized number is from 2 to 30.