A method and apparatus for applying network coding in multi-user (MU) multiple-input multiple-output (MIMO) control signaling are disclosed. After a pair of wireless transmit/receive units (WTRUs) transmit channel state information (CSI) to an evolved Node-B (eNodeB), each of the WTRUs receive network coded information from the eNodeB, including the CSI transmitted by both of the WTRUs, and decode the network coded information. The WTRUs transmit CSI on a scheduled basis, and store CSI that was previously transmitted. Each of the WTRUs measure the amount of time that pass since they transmitted CSI, and use the transmitted CSI to decode the network coded information on the condition that the measured time does not exceed a predetermined threshold. If the measured time exceeds the predetermined threshold, the stored CSI is used to decode the network coded information.