发明申请
US20100179092A1 HUMAN COMPLEMENT C3 DERIVATIVES WITH COBRA VENOM FACTOR-LIKE FUNCTION
审中-公开
人体补充C3衍生物与COBRA体温因子类似功能
- 专利标题： HUMAN COMPLEMENT C3 DERIVATIVES WITH COBRA VENOM FACTOR-LIKE FUNCTION
- 专利标题（中）： 人体补充C3衍生物与COBRA体温因子类似功能
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申请号： US12513665申请日： 2007-11-15
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公开(公告)号： US20100179092A1公开(公告)日： 2010-07-15
- 发明人: David C. Fritzinger , Carl-Wilhelm Vogel
- 申请人： David C. Fritzinger , Carl-Wilhelm Vogel
- 国际申请： PCT/US07/24163 WO 20071115
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; C07K14/00 ; C07H21/04 ; A61P43/00 ; C12N15/63 ; C12P21/02 ; C12N5/10 ; C12N1/21 ; C12N1/19
摘要：
The invention provides modified human complement C3 proteins, comprising a human C3 protein, wherein amino acid residues in the human C3 protein are substituted with a corresponding portion of a Cobra Venom Factor (CVF) protein, and wherein one or more amino acid residues in the CVF portion of the modified human complement C3 protein are further modified.