A sacral mesh fixation device and method of use for sacral colpopexy. The sacral mesh fixation device comprises multiple hinged sections pivoted together at opposite ends and adapted to clamp one or more strips of sacral mesh there between. A latching mechanism is provided for releasably latching the opposing sections shut, thereby releasably clamping the sacral mesh to allow verification of tension. A sequential latching mechanism is provided to fixedly lock the fixation device to the sacral mesh by latching the remaining section to the prior sections. At least one of the sections may be sutured to tissue and the sacral mesh inserted between the sections and releasably clamped in place, thereby releasably affixing the mesh to the tissue or fixedly locking the mesh to the device thereby permanently locking the mesh to the tissue. To use the device, a single mesh fixation device or a plurality of mesh fixation devices may be introduced through a trocar into the abdomen, positioned in a single or supporting array, and sutured to surrounding tissue. The sacral mesh is then clamped between opposing sections of the mesh fixation device(s), thereby temporarily suspending the mesh in a sling. However, the fixation devices can be reopened to facilitate easy readjustment and repositioning of the mesh sling to achieve the proper tension and position or fixedly locked for permanent support of the mesh.