- 专利标题: RNAi Inhibition of Alpha-ENaC Expression
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申请号: US12683146申请日: 2010-01-06
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公开(公告)号: US20100190714A1公开(公告)日: 2010-07-29
- 发明人: Gino VAN HEEKE , Emma Hickman , Henry Luke Danahay , Pamela Tan , Anke Geick , Hans-Peter Vornlocher
- 申请人: Gino VAN HEEKE , Emma Hickman , Henry Luke Danahay , Pamela Tan , Anke Geick , Hans-Peter Vornlocher
- 专利权人: Novatis AG
- 当前专利权人: Novatis AG
- 优先权: EP07110376.6 20070615; EP07114265.7 20090813
- 主分类号: A61K38/40
- IPC分类号: A61K38/40 ; A61K31/713 ; C07H21/02 ; A61P11/00
摘要:
The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides.
公开/授权文献
- US09074212B2 RNAi inhibition of alpha-ENaC expression 公开/授权日:2015-07-07
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