发明申请
- 专利标题： Tricyclic Compounds As Modulators of TNF-alpha Synthesis
- 专利标题（中）： 三环化合物作为TNF-α合成的调节剂
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申请号： US12532861申请日： 2009-01-23
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公开(公告)号： US20100190808A1公开(公告)日： 2010-07-29
- 发明人: Adnan M. M. Mjalli , Bapu Gaddam , Dharmo Rao , Matthew Kostura , Mustafa Guzel
- 申请人： Adnan M. M. Mjalli , Bapu Gaddam , Dharmo Rao , Matthew Kostura , Mustafa Guzel
- 申请人地址： US NC High Point
- 专利权人： HIGH POINT PHARMACEUTICALS, LLC.
- 当前专利权人： HIGH POINT PHARMACEUTICALS, LLC.
- 当前专利权人地址： US NC High Point
- 国际申请： PCT/US2009/031819 WO 20090123
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D239/70 ; A61P29/00 ; A61P19/02 ; A61P3/10 ; A61P1/00 ; A61P25/00
摘要：
The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-alpha or by PDE4, including but not limited to rheumatoid arthritis.
公开/授权文献
- US07964608B2 Tricyclic compounds as modulators of TNF-α synthesis 公开/授权日：2011-06-21
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