发明申请
- 专利标题： USE OF A PEPTIDE AS A THERAPEUTIC AGENT
- 专利标题（中）： 使用作为治疗剂的肽
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申请号： US12677266申请日： 2008-09-09
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公开(公告)号： US20100197587A1公开(公告)日： 2010-08-05
- 发明人: Dorian Bevec , Fabio Cavalli , Vera Cavalli , Gerald Bacher
- 申请人： Dorian Bevec , Fabio Cavalli , Vera Cavalli , Gerald Bacher
- 优先权： EP07017756.3 20070911
- 国际申请： PCT/EP08/07577 WO 20080909
- 主分类号： A61K38/17
- IPC分类号： A61K38/17 ; A61P3/00 ; A61P9/00 ; A61P11/00 ; A61P25/28 ; A61P31/00 ; A61P35/00 ; A61P37/00
摘要：
The present invention is directed to the use of the peptide compound His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-Arg-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-Arg-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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