Invention Application
US20100197898A1 USE OF URSOLIC ACID SAPONIN,OLEANOLIC ACID SAPONIN IN PREPARATION OF INCREASING LEUCOCYTES AND/OR PLATELET MEDICINE
有权
尿酸SAPONIN，OLEANOLIC ACID SAPONIN在制备增加白细胞介素和/或药物的药物中的应用
- Patent Title: USE OF URSOLIC ACID SAPONIN,OLEANOLIC ACID SAPONIN IN PREPARATION OF INCREASING LEUCOCYTES AND/OR PLATELET MEDICINE
- Patent Title (中): 尿酸SAPONIN，OLEANOLIC ACID SAPONIN在制备增加白细胞介素和/或药物的药物中的应用
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Application No.: US12523314Application Date: 2008-01-16
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Publication No.: US20100197898A1Publication Date: 2010-08-05
- Inventor: Bing Guang , Junjian Liu , Guangxin Dong , xiangyang Peng , xiaoxia Gong , zhen Huang , Meirong Zhou , Wei Zhan , Jufang Yan , Yu Huang , Dongguang Qin , jianxin Jl , Bogang Li
- Applicant: Bing Guang , Junjian Liu , Guangxin Dong , xiangyang Peng , xiaoxia Gong , zhen Huang , Meirong Zhou , Wei Zhan , Jufang Yan , Yu Huang , Dongguang Qin , jianxin Jl , Bogang Li
- Applicant Address: CN Chengdu
- Assignee: Chengdu Di'Ao Jiuhong Pharmaceutical Factory
- Current Assignee: Chengdu Di'Ao Jiuhong Pharmaceutical Factory
- Current Assignee Address: CN Chengdu
- Priority: CN200710048277.1 20070116; CN200710048278.6 20070116
- International Application: PCT/CN2008/000107 WO 20080116
- Main IPC: C07H15/256
- IPC: C07H15/256
Abstract:
The invention provides the use of ursolic acid saponin and oleanolic acid saponin of formula (I) in preparing medicaments for increasing leucocytes and/or platelets. The invention also provides a pharmaceutical composition containing the same compound. The invention utilizes the cheap and accessible ursolic acid and oleanolic acid which are widely present in natural plants as raw materials, introduces monosaccharyls or oligosaccharyls by structural modification. It is proved by pharmacological tests that the compound of formula (I) have an activity of obviously increasing leucocytes and/or platelets.
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