- 专利标题: Stent Coating For Eluting Medication
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申请号: US12755777申请日: 2010-04-07
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公开(公告)号: US20100198335A1公开(公告)日: 2010-08-05
- 发明人: Robert C. O'Brien , Christine A. Frysz
- 申请人: Robert C. O'Brien , Christine A. Frysz
- 申请人地址: US NY Clarence
- 专利权人: Greatbatch Ltd.
- 当前专利权人: Greatbatch Ltd.
- 当前专利权人地址: US NY Clarence
- 主分类号: A61F2/86
- IPC分类号: A61F2/86 ; B23P25/00
摘要:
A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.
公开/授权文献
- US08367151B2 Stent coating for eluting medication 公开/授权日:2013-02-05
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