A shoe sole and a shoe comprising such a shoe sole are described, with the shoe sole being equipped with integrated anti-slipping elements which are adjustable between an inactive position and an active position by means of a central actuation unit. This arrangement is characterized in that the anti-slipping elements, which in particular have the form of spikes, are respectively supported in individual functional units and are axially adjustable between their active and inactive positions through rotation by the central actuation unit via at least one flexible drive element.