发明申请
US20100210651A1 ISOXAZOLE-ISOXAZOLES AND ISOXAZOLE-ISOTHIAZOLES
有权
ISOXAZOLE-ISOXAZOLES和ISOXAZOLE-ISOTHIAZOLES
- 专利标题： ISOXAZOLE-ISOXAZOLES AND ISOXAZOLE-ISOTHIAZOLES
- 专利标题（中）： ISOXAZOLE-ISOXAZOLES和ISOXAZOLE-ISOTHIAZOLES
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申请号： US12704548申请日： 2010-02-12
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公开(公告)号： US20100210651A1公开(公告)日： 2010-08-19
- 发明人: Maria-Clemencia Hernandez , Roland Jakob-Roetne , Matthew C. Lucas , Andrew Thomas
- 申请人： Maria-Clemencia Hernandez , Roland Jakob-Roetne , Matthew C. Lucas , Andrew Thomas
- 优先权： EP09153162.4 20090219
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D413/06 ; A61K31/42 ; C07D413/14 ; A61K31/454 ; A61P25/28
摘要：
The present invention is concerned with isoxazole-isoxazoles and isoxazole-isothiazoles of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as cognitive enhancers or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.
公开/授权文献
- US08173652B2 Isoxazole-isoxazoles and isoxazole-isothiazoles 公开/授权日：2012-05-08
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