发明申请
- 专利标题： N-SUBSTITUTED AZAINDOLES AND METHODS OF USE
- 专利标题（中）： N-取代的胺和其使用方法
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申请号： US12664303申请日： 2008-06-11
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公开(公告)号： US20100216768A1公开(公告)日： 2010-08-26
- 发明人: Hazel Joan Dyke , Stephen Price , Karen Williams
- 申请人： Hazel Joan Dyke , Stephen Price , Karen Williams
- 国际申请： PCT/US08/66570 WO 20080611
- 主分类号： A61K31/50
- IPC分类号： A61K31/50 ; C07D471/04 ; A61K31/437 ; C07D487/04 ; A61P29/00
摘要：
The invention relates to N-substituted azaindolyl compounds of Formula I with anti-cancer and/or anti-inflammatory activity and more specifically to N-substituted azaindolyl compounds which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.
公开/授权文献
- US08258152B2 N-substituted azaindoles and methods of use 公开/授权日：2012-09-04
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