发明申请
- 专利标题： RHO-KINASE INHIBITORS
- 专利标题（中）： RHO-激酶抑制剂
-
申请号： US12688428申请日： 2010-01-15
-
公开(公告)号： US20100216789A1公开(公告)日： 2010-08-26
- 发明人: Dhanapalan NAGARATHNAM , Uday Khire , Davoud Asgari , Jianxing Shao , Xiao-Gao Liu , Chunguang Wang , Barry Hart , Olaf Weber , Mark Lynch , Lei Zhang , Lei Wang
- 申请人： Dhanapalan NAGARATHNAM , Uday Khire , Davoud Asgari , Jianxing Shao , Xiao-Gao Liu , Chunguang Wang , Barry Hart , Olaf Weber , Mark Lynch , Lei Zhang , Lei Wang
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D495/04 ; A61K31/5377 ; A61K31/53 ; C07D513/04 ; A61P9/12 ; A61P9/10 ; A61P15/10
摘要：
Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
信息查询
IPC分类:
