发明申请
- 专利标题： HETEROARYL SUBSTITUTED PYRIDAZINONE DERIVATIVES
- 专利标题（中）： 异氟醚取代的吡咯烷酮衍生物
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申请号： US12705988申请日： 2010-02-16
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公开(公告)号： US20100216793A1公开(公告)日： 2010-08-26
- 发明人: Daniela Alberati , Matthias Koerner , Bernd Kuhn , Jens-Uwe Peters , Rose Maria Rodriguez Sarmiento , Mark Rogers-Evans , Markus Rudolph
- 申请人： Daniela Alberati , Matthias Koerner , Bernd Kuhn , Jens-Uwe Peters , Rose Maria Rodriguez Sarmiento , Mark Rogers-Evans , Markus Rudolph
- 优先权： EP09153391.9 20090223
- 主分类号： A61K31/501
- IPC分类号： A61K31/501 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; A61K31/5377
摘要：
The present invention is concerned with novel pyridazinone derivatives of formula (I) wherein R1, R2, R3 and R4 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit PDE10A and can be used as pharmaceuticals.
公开/授权文献
- US09187455B2 Substituted pyridazines as PDE10A inhibitors 公开/授权日：2015-11-17
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