发明申请
US20100216845A1 ISOXAZOLES / O-PYRIDINES WITH ETHYL AND ETHENYL LINKER
有权
乙烯和乙烯基连接的ISOXAZOLES / O-吡啶
- 专利标题： ISOXAZOLES / O-PYRIDINES WITH ETHYL AND ETHENYL LINKER
- 专利标题（中）： 乙烯和乙烯基连接的ISOXAZOLES / O-吡啶
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申请号： US12706722申请日： 2010-02-17
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公开(公告)号： US20100216845A1公开(公告)日： 2010-08-26
- 发明人: Bernd Buettelmann , Matthew C. Lucas , Andrew Thomas
- 申请人： Bernd Buettelmann , Matthew C. Lucas , Andrew Thomas
- 优先权： EP09153575.7 20090225
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; C07D413/06 ; C07D413/14
摘要：
The present invention is concerned with novel isoxazole-pyridines of formula I wherein R1, R2, R3 and L are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of the present invention have affinity and selectivity for GABA A α5 receptor. Further the present invention is concerned with the manufacture of the active compounds of formula I, pharmaceutical compositions containing them and their use as pharmaceutical agents.
公开/授权文献
- US08389550B2 Isoxazoles / O-pyridines with ethyl and ethenyl linker 公开/授权日：2013-03-05
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