发明申请
- 专利标题： ANTAGONIZING SIGNAL TRANSDUCTION IN DORSAL ROOT GANGLION CELLS IN A SUBJECT WITH IL-31 ANTAGONISTS
- 专利标题（中）： 拮抗IL-31拮抗剂的脊髓背根神经节细胞信号转导
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申请号： US12395095申请日： 2009-02-27
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公开(公告)号： US20100221244A1公开(公告)日： 2010-09-02
- 发明人: Yue Yao , Janine Bilsborough
- 申请人： Yue Yao , Janine Bilsborough
- 专利权人： ZymoGenetics, Inc.
- 当前专利权人： ZymoGenetics, Inc.
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P25/00
摘要：
Use of antagonists to IL-31 are used to treat inflammation and pain by inhibiting, preventing, reducing, minimizing, limiting or minimizing stimulation in neuronal tissues. Such antagonists include antibodies and fragments, derivative, or variants thereof. Symptoms such as pain, tingle, sensitization, tickle associated with neuropathies are ameliorated.
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