发明申请
- 专利标题: CHO-K1 CELL LINE
- 专利标题(中): CHO-K1细胞系
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申请号: US12681783申请日: 2008-10-13
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公开(公告)号: US20100221781A1公开(公告)日: 2010-09-02
- 发明人: Erhard Kopetzki , Ursula Schwarz
- 申请人: Erhard Kopetzki , Ursula Schwarz
- 优先权: EP07019999.7 20071012
- 国际申请: PCT/EP08/08636 WO 20081013
- 主分类号: C12P21/06
- IPC分类号: C12P21/06 ; C12N5/10
摘要:
The current invention reports a CHO-K1 cell, characterized in that said CHO-K 1 cell is derived from CHO-K1 cell deposited as ATCC CCL-61, grows in suspension, requires no glutamine, no insulin, and no growth factors in the cultivation medium for growth, whereby said CHO-K1 cell is not modified compared to the deposited CHO-K1 cell ATCC CCL-61 cell line by the introduction, deletion, or inactivation of a nucleic acid. Also reported are a method for obtaining said CHO-K1 cell and a method for the production of a heterologous polypeptide using such a CHO-K1 cell according to the invention.