发明申请
US20100233240A1 CORNEAL ENDOTHELIAL PREPARATION WHICH ENABLES CELLS TO GROW IN VIVO
审中-公开
角膜内皮细胞在体内生长的脊髓内皮制剂
- 专利标题： CORNEAL ENDOTHELIAL PREPARATION WHICH ENABLES CELLS TO GROW IN VIVO
- 专利标题（中）： 角膜内皮细胞在体内生长的脊髓内皮制剂
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申请号： US12161433申请日： 2007-01-18
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公开(公告)号： US20100233240A1公开(公告)日： 2010-09-16
- 发明人: Noriko Koizumi , Shigeru Kinoshita , Yuji Sakamoto
- 申请人： Noriko Koizumi , Shigeru Kinoshita , Yuji Sakamoto
- 申请人地址： JP Osaka-shi, Osaka
- 专利权人： SENJU PHARMACEUTICAL CO., LTD.
- 当前专利权人： SENJU PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： JP Osaka-shi, Osaka
- 优先权： JP2006-011521 20060119
- 国际申请： PCT/JP2007/050657 WO 20070118
- 主分类号： A61F2/14
- IPC分类号： A61F2/14 ; A61K35/44 ; A61P27/02
摘要：
The present invention provides a graft more suitable for the transplantation of corneal endothelial cells and an application method thereof. Specifically, the present invention provides a corneal endothelial preparation capable of cell proliferation in vivo, which contains a substrate and a corneal endothelial cell layer cultured on the substrate, and a treatment method of a disease selected from the group consisting of bullous keratopathy, corneal edema, corneal leukoma and corneal endothelial inflammation, which includes a step of transplanting the preparation to patients. As the substrate, collagen is used.
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