发明申请
US20100233265A1 MATRIX-TYPE PHARMACEUTICAL SOLID PREPARATION 有权
MATRIX型药物固体制剂

  • 专利标题: MATRIX-TYPE PHARMACEUTICAL SOLID PREPARATION
  • 专利标题(中): MATRIX型药物固体制剂
  • 申请号: US12738543
    申请日: 2008-09-26
  • 公开(公告)号: US20100233265A1
    公开(公告)日: 2010-09-16
  • 发明人: Kai Suzuki
  • 申请人: Kai Suzuki
  • 优先权: JP2007-272700 20071019
  • 国际申请: PCT/JP2008/067996 WO 20080926
  • 主分类号: A61K31/70
  • IPC分类号: A61K31/70 A61K9/10
MATRIX-TYPE PHARMACEUTICAL SOLID PREPARATION
摘要:
The present invention aims to provide a matrix-type solid preparation that has high-level release controllability for suppressing drug release in the upper gastrointestinal tract and accelerating drug release in the lower gastrointestinal tract, and that solves of all the above drawbacks caused by combining a plasticizer. The present invention provides a matrix-type pharmaceutical solid preparation that contains: (a) a methacrylic acid-based enteric polymer; and (b) a sugar and/or a sugar alcohol, wherein 1 g of the sugar and/or the sugar alcohol can be dissolved in not more than 4 g of water at a water temperature of 20 to 25° C.
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