发明申请
US20100239554A1 EXTENDED RECOMBINANT POLYPEPTIDES AND COMPOSITIONS COMPRISING SAME
有权
扩展的重组多聚体和包含相同的组合物
- 专利标题： EXTENDED RECOMBINANT POLYPEPTIDES AND COMPOSITIONS COMPRISING SAME
- 专利标题（中）： 扩展的重组多聚体和包含相同的组合物
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申请号： US12699761申请日： 2010-02-03
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公开(公告)号： US20100239554A1公开(公告)日： 2010-09-23
- 发明人: Volker Schellenberger , Joshua Silverman , Chia-wel Wang , Benjamin Spink , Willem P. Stemmer , Nathan C. Geething , Wayne To , Jeffrey L. Cleland
- 申请人： Volker Schellenberger , Joshua Silverman , Chia-wel Wang , Benjamin Spink , Willem P. Stemmer , Nathan C. Geething , Wayne To , Jeffrey L. Cleland
- 专利权人： Amunix Inc. a Delaware Corporation
- 当前专利权人： Amunix Inc. a Delaware Corporation
- 主分类号： A61K38/48
- IPC分类号： A61K38/48 ; C07K14/46 ; C12N9/64 ; C07K14/61 ; C07H21/04 ; C12N15/63 ; C12N1/21 ; C12N5/10 ; A61P3/10 ; A61P3/04 ; A61P3/08 ; A61P3/06 ; A61P7/04 ; A61P9/12 ; A61P9/10 ; A61P5/06 ; A61P1/04 ; A61P19/02 ; A61K38/27 ; A61K38/16 ; A61K38/26 ; A61K38/23 ; A61K38/31 ; A61P5/22 ; A61K38/22 ; A61K38/18 ; A61K38/36
摘要：
The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.