发明申请
- 专利标题: TUBULYSINS AND PROCESSES FOR PREPARING
- 专利标题(中): 用于制备的管状体和方法
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申请号: US12739579申请日: 2008-10-23
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公开(公告)号: US20100240701A1公开(公告)日: 2010-09-23
- 发明人: Iontcho Radoslavov Vlahov , Christopher Paul Leamon , Yu Wang
- 申请人: Iontcho Radoslavov Vlahov , Christopher Paul Leamon , Yu Wang
- 申请人地址: US IN West Lafayette
- 专利权人: ENDOCYTE, INC.
- 当前专利权人: ENDOCYTE, INC.
- 当前专利权人地址: US IN West Lafayette
- 国际申请: PCT/US08/80948 WO 20081023
- 主分类号: A61K31/4545
- IPC分类号: A61K31/4545 ; C07D417/12 ; A61K31/454 ; C07D417/14 ; A61P31/12
摘要:
Processes are described for the preparation of tubulysins. The processes are useful for preparing predetermined mixtures of tubulysins, preparing single tubulysins from mixtures of tubulysins, and for converting one tubulysin into a different tubulysin. The tubulysins described herein are useful in treating diseases and disease states that include pathogenic cell populations.
公开/授权文献
- US09187521B2 Tubulysins and processes for preparing 公开/授权日:2015-11-17