发明申请
- 专利标题： SUBSTITUTED PIPERAZINES AS CB1 ANTAGONISTS
- 专利标题（中）： 取代的PIPERAZINES作为CB1拮抗剂
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申请号： US12665250申请日： 2008-06-25
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公开(公告)号： US20100249144A1公开(公告)日： 2010-09-30
- 发明人: Duane Eugene Demong , Michael W. Miller , Eric J. Gilbert , Jack D. Scott , Andrew Stamford , William J. Greenlee , Chander Shekher Celly
- 申请人： Duane Eugene Demong , Michael W. Miller , Eric J. Gilbert , Jack D. Scott , Andrew Stamford , William J. Greenlee , Chander Shekher Celly
- 国际申请： PCT/US08/07867 WO 20080625
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D241/04 ; A61K31/495 ; C07D401/06 ; A61P25/28 ; A61P25/16 ; A61P25/06 ; A61P25/08 ; A61P25/02 ; A61P25/18 ; A61P25/22 ; A61P25/32 ; A61P25/34 ; A61P35/00 ; A61P1/00 ; A61P1/08 ; A61P1/12 ; A61P3/10 ; A61P3/04 ; A61P29/00 ; A61P15/10
摘要：
Compounds of Formula (I) or pharmaceutically acceptable salts, solvates, or esters thereof, are useful in treating diseases or conditions mediated by CB1 receptors, such as metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, addiction (e.g., smoking cessation), gastrointestinal disorders, and cardiovascular conditions.
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