发明申请
- 专利标题： Method for purifying the rabies virus
- 专利标题（中）： 纯化狂犬病病毒的方法
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申请号： US12756590申请日： 2010-04-08
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公开(公告)号： US20100260798A1公开(公告)日： 2010-10-14
- 发明人: Virginie Fabre , Céline Rocca , Pierre Riffard , Eric Calvosa
- 申请人： Virginie Fabre , Céline Rocca , Pierre Riffard , Eric Calvosa
- 申请人地址： FR Lyon
- 专利权人： SANOFI PASTEUR
- 当前专利权人： SANOFI PASTEUR
- 当前专利权人地址： FR Lyon
- 优先权： FR0952310 20090408
- 主分类号： A61K39/205
- IPC分类号： A61K39/205 ; A61P31/14 ; C12N7/02 ; C12N7/06
摘要：
The subject of the invention is a method for purifying the rabies virus, comprising a single ion-exchange chromatography step, said step being cation exchange chromatography according to which: a) the supernatant of a culture of cells infected with this virus is brought into contact with a cation exchange chromatography support comprising a polymethacrylate matrix onto which sulfoisobutyl groups have been grafted such that the rabies virus binds to this support, and; b) the virus is eluted from its support.
公开/授权文献
- US08961997B2 Method for purifying the rabies virus 公开/授权日：2015-02-24