发明申请
US20100267793A1 METHOD OF TREATMENT USING N3 ALKYLATED BENZIMIDAZOLE DERIVATIVES AS MEK INHIBITORS
有权
使用N 3烷氧基苯并咪唑衍生物作为MEK抑制剂处理的方法
- 专利标题： METHOD OF TREATMENT USING N3 ALKYLATED BENZIMIDAZOLE DERIVATIVES AS MEK INHIBITORS
- 专利标题（中）： 使用N 3烷氧基苯并咪唑衍生物作为MEK抑制剂处理的方法
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申请号： US12824521申请日： 2010-06-28
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公开(公告)号： US20100267793A1公开(公告)日： 2010-10-21
- 发明人: Eli M. Wallace , Joseph P. Lyssikatos , Allison L. Marlow , T. Brian Hurley
- 申请人： Eli M. Wallace , Joseph P. Lyssikatos , Allison L. Marlow , T. Brian Hurley
- 申请人地址： US CO Boulder
- 专利权人： ARRAY BIOPHARMA INC.
- 当前专利权人： ARRAY BIOPHARMA INC.
- 当前专利权人地址： US CO Boulder
- 主分类号： A61K31/4184
- IPC分类号： A61K31/4184 ; A61P35/04 ; A61P17/00
摘要：
Disclosed are methods of treating a hyperproliferative disorder or a disease related to vasculogenesis or angiogenesis in a mammal, comprising administering to said mammal an effective amount of a compound of the formula or a pharmaceutically accepted salt thereof, wherein A, R1, R2, R7, R8, and R9 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals.
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