发明申请
- 专利标题: PROCESS FOR PRODUCING LAUROLACTAM
- 专利标题(中): 生产乳酸菌的方法
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申请号: US12744675申请日: 2008-11-19
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公开(公告)号: US20100267944A1公开(公告)日: 2010-10-21
- 发明人: Junichi Kugimoto , Joji Kawai , Hideo Shimomura , Ryouta Yasumatsu , Nobuhiro II
- 申请人: Junichi Kugimoto , Joji Kawai , Hideo Shimomura , Ryouta Yasumatsu , Nobuhiro II
- 申请人地址: JP Yamaguchi
- 专利权人: UBE INDUSTRIES, LTD.
- 当前专利权人: UBE INDUSTRIES, LTD.
- 当前专利权人地址: JP Yamaguchi
- 优先权: JP2007-308746 20071129
- 国际申请: PCT/JP2008/071044 WO 20081119
- 主分类号: C07D225/02
- IPC分类号: C07D225/02
摘要:
Provided is a process for efficiently producing laurolactam by simple steps from cyclododecanone and hydroxylamine. This production process comprises the steps of: (a) reacting cyclododecanone with hydroxylamine in an aqueous solution in the presence of an oxime-formation solvent to produce cyclododecanone oxime; (b) separating the reaction mixture obtained after the oxime-forming step into an oil and an aqueous phases and collecting a solution of cyclododecanone oxime of the oil phase; (c) removing a part or all of the oxime-formation solvent and dissolved water from the solution of cyclododecanone oxime which is collected as an oil phase in the oil/aqueous phase separation step, whereby preparing a solution containing a rearrangement solvent to be used in a rearrangement reaction in a later step and the cyclododecanone oxime; (d) producing laurolactam from cyclododecanone oxime by rearrangement reaction using an aromatic-ring containing compound as a rearrangement catalyst; and (e) separating and removing the rearrangement solvent and the rearrangement catalyst from the reaction mixture after the rearrangement step, and purifying the laurolactam.
公开/授权文献
- US08309714B2 Process for producing laurolactam 公开/授权日:2012-11-13
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