发明申请
US20100278829A1 DUAL INHIBITION OF IMMUNOPHILIN/CYCLOPHILIN FAMILY MEMBERS AND EMMPRIN IMMUNOGLOBULIN RECEPTOR SUPERFAMILY MEMBERS
审中-公开
免疫球蛋白/环磷酰胺家族成员和EMMPRIN免疫抑制蛋白受体超家族成员的双重抑制
- 专利标题： DUAL INHIBITION OF IMMUNOPHILIN/CYCLOPHILIN FAMILY MEMBERS AND EMMPRIN IMMUNOGLOBULIN RECEPTOR SUPERFAMILY MEMBERS
- 专利标题（中）： 免疫球蛋白/环磷酰胺家族成员和EMMPRIN免疫抑制蛋白受体超家族成员的双重抑制
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申请号： US12701560申请日： 2010-02-06
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公开(公告)号： US20100278829A1公开(公告)日： 2010-11-04
- 发明人: Carl Keith Edwards, III , Asokan Rengasamy , Mayumi Fujita , Elan Z. Eisenmesser , Karen R. Jonscher , David A. Norris , Li Li
- 申请人： Carl Keith Edwards, III , Asokan Rengasamy , Mayumi Fujita , Elan Z. Eisenmesser , Karen R. Jonscher , David A. Norris , Li Li
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K31/713 ; A61P17/06 ; A61P29/00 ; A61P35/00 ; A61P9/00
摘要：
The present disclosure provides methods and compositions for modulating an adaptive immune response without significantly affecting an innate immunity response in a subject by modulating a combination of an Immunophilin/Cyclophilin Family Member and an EMMPRIN Immunoglobulin Receptor Superfamily Member. The present invention also provides methods and compositions for treating a variety of clinical conditions by modulating an Immunophilin/Cyclophilin Family Member and an EMMPRIN Immunoglobulin Receptor Superfamily Member.
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