Invention Application
- Patent Title: MONOSEBACATE OF PYRAZOLE DERIVATIVE
- Patent Title (中): 吡唑衍生物的单体
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Application No.: US12810476Application Date: 2008-12-24
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Publication No.: US20100279962A1Publication Date: 2010-11-04
- Inventor: Hideki Takeuchi , Eiji Tsuru
- Applicant: Hideki Takeuchi , Eiji Tsuru
- Applicant Address: JP Matsumoto-shi, Nagano
- Assignee: KISSEI PHARMACEUTICAL CO., LTD.
- Current Assignee: KISSEI PHARMACEUTICAL CO., LTD.
- Current Assignee Address: JP Matsumoto-shi, Nagano
- Priority: JP2007-337985 20071227
- International Application: PCT/JP2008/073405 WO 20081224
- Main IPC: A61K31/7056
- IPC: A61K31/7056 ; C07H17/02 ; A61P3/10

Abstract:
The present invention provides a novel form of 3-(3-{4-[3-(β-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethylpropionamide with improved storage stability. Since bis[3-(3-{4-[3-(β-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethylpropionamide] monosebacate has extremely excellent storage stability, it is useful as a drug substance. Furthermore, it shows an extremely good crystalline property and can be purified by a convenient method, and therefore is suitable for the industrial preparation.
Public/Granted literature
- US08399418B2 Monosebacate of pyrazole derivative Public/Granted day:2013-03-19
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