发明申请
- 专利标题: TAT SIGNAL PEPTIDES FOR PRODUCING PROTEINS IN PROKARYOTES
- 专利标题(中): 用于生产蛋白质的TAT信号肽
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申请号: US12664357申请日: 2008-06-02
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公开(公告)号: US20100285567A1公开(公告)日: 2010-11-11
- 发明人: Kai Bao , Fernando Valle
- 申请人: Kai Bao , Fernando Valle
- 国际申请: PCT/US08/06943 WO 20080602
- 主分类号: C12N9/14
- IPC分类号: C12N9/14 ; C12N1/21 ; C12N15/63 ; C07H21/04
摘要:
This invention provides polynucleotides encoding TAT fusion proteins, and methods for producing proteins of interest in a host cell. In particular, the present invention relates to polynucleotides, vectors, polypeptides and methods for expressing organophosphate-degrading enzymes e.g. organophosphorus hydrolase (OPH) in host cell, such as a Streptomyces species host cell.
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