An endoscope is provided for observing an object. The endoscope includes a microfluidic device defining a well therein and a lens disposed in the well of the microfluidic device. The lens has a tunable focal length. A tuning structure is provided for tuning the focal length of the lens in response to a predetermined stimulus and an illumination fiber may be positioned adjacent to the lens for illuminating the object. An activation fiber bundle is adjacent to the tuning structure for providing the predetermined stimulus to the tuning structure. The image acquisition fiber bundle is in alignment with the lens for receiving an image therefrom.