发明申请
US20100291689A1 Lanthanide Complexes as Fluorescent Indicators for Neutral Sugars and Cancer Diagnosis
审中-公开
镧系复合物作为中性糖和癌症诊断的荧光指示剂
- 专利标题： Lanthanide Complexes as Fluorescent Indicators for Neutral Sugars and Cancer Diagnosis
- 专利标题（中）： 镧系复合物作为中性糖和癌症诊断的荧光指示剂
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申请号： US12293483申请日： 2007-03-14
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公开(公告)号： US20100291689A1公开(公告)日： 2010-11-18
- 发明人: Robert M. Strongin , Onur Alptürk , Oleksandr Rusin , Sayo O. Fakayode , Jorge O. Escobedo Cordova , Weihua Wang , Isiah M. Warner , William E. Crowe , Vladimir Král
- 申请人： Robert M. Strongin , Onur Alptürk , Oleksandr Rusin , Sayo O. Fakayode , Jorge O. Escobedo Cordova , Weihua Wang , Isiah M. Warner , William E. Crowe , Vladimir Král
- 申请人地址： US LA Baton Rouge CZ Prague 6
- 专利权人： BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY & AGRICULTURAL AND MECHANICAL COLLEGE,INSTITUTE OF CHEMICAL TECHNOLOGY
- 当前专利权人： BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY & AGRICULTURAL AND MECHANICAL COLLEGE,INSTITUTE OF CHEMICAL TECHNOLOGY
- 当前专利权人地址： US LA Baton Rouge CZ Prague 6
- 国际申请： PCT/US2007/063943 WO 20070314
- 主分类号： G01N33/48
- IPC分类号： G01N33/48 ; G01N33/92 ; G01N33/574 ; C07F5/00 ; C07C251/00
摘要：
A group of water-soluble salophene-lanthanide complexes and other salophene-metal complexes are useful for purposes including: (i) detecting neutral carbohydrates at physiologically-relevant pH, (ii) the selective detection of gangliosides, and (iii) the selective detection of lysophosphatidic acid (LPA) in the presence of phosphatidic acid. The selective detection of LPA is useful in diagnosing ovarian and other cancers.