发明申请
US20100297078A1 METHOD FOR PRODUCING A HYDROXYALKYL STARCH DERIVATIVE WITH TWO LINKERS
审中-公开
用两个连接体生产羟基烷基淀粉衍生物的方法
- 专利标题: METHOD FOR PRODUCING A HYDROXYALKYL STARCH DERIVATIVE WITH TWO LINKERS
- 专利标题(中): 用两个连接体生产羟基烷基淀粉衍生物的方法
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申请号: US12747972申请日: 2008-12-15
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公开(公告)号: US20100297078A1公开(公告)日: 2010-11-25
- 发明人: Frank Hacket , Wolfram Eichner , Helmut Knoller , Andreas Mitsch , Martin Schimmel , Norbert Zander , Franziska Hauschild
- 申请人: Frank Hacket , Wolfram Eichner , Helmut Knoller , Andreas Mitsch , Martin Schimmel , Norbert Zander , Franziska Hauschild
- 申请人地址: DE Bad Homburg
- 专利权人: Fresenius Kabi Deutschland GmbH
- 当前专利权人: Fresenius Kabi Deutschland GmbH
- 当前专利权人地址: DE Bad Homburg
- 优先权: EP07024351.4 20071214
- 国际申请: PCT/EP2008/010659 WO 20081215
- 主分类号: A61K38/21
- IPC分类号: A61K38/21 ; C08B31/12 ; C07K14/56 ; C07K14/505 ; C07K14/535 ; C07H7/02 ; C07K1/00 ; A61K38/18 ; A61P35/00 ; A61P35/02 ; A61P1/16 ; A61P7/06 ; A61P13/12 ; A61P31/18
摘要:
A method of producing a hydroxyalkyl starch (HAS) derivative, comprising a) reacting optionally oxidized hydroxyalkyl starch with a compound (D) comprising at least two functional groups —O—NH2 or a salt thereof, and b) reacting the hydroxyalkyl starch derivative obtained in step a) with a compound (L) comprising at least two functional groups W1 and W2 independently selected from the group consisting of an aldehyde group, a suitably protected aldehyde group, a keto group, and a suitably protected keto group.